Methoxyeugenol-O-glucuronide

Methoxyeugenol-O-glucuronide is a metabolite of methoxyeugenol and elemicin.

Glucuronosyltransferase (UGT) readily attacks methoxyeugenol (a metabolite of elemicin) on the 4 hydroxy position of the benzene ring producing methoxyeugenol-O-glucuronide. This action reduces the lipid solubility from methoxyeugenol's XLogP3-AA of 2.6 down to chavicol-O-glucuronide's XLogP3 of 1.02.

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Chemical Properties

Molecular Weight: 370.39[g/mol]
Formula: C17H22O9
XLogP3: 1.02 [1]
Canonical SMILES: C=CCC1=CC(=C(C(=C1)OC)OC2C([C@H](C([C@H](O2)C(=O)O)O)O)O)OC

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See Also

• Elemicin
• Glucuronosyltransferase (UGT)
• Methoxyeugenol
• Methoxyeugenol-O-sulfate
• Oilahuasca Activation
• Sulfotransferase (SULT)

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Bibliography

1. XLogP3 values calculated using the Virtual Computational Chemistry Laboratory's

On-line Lipophilicity(logP), Water Solubility(LogS) & pKa Prediction calculator.