
This allylbenzene is found in betel leaf essential oil. It is reported to have stimulant effects. It is a major metabolite of safrole[1], and also a metabolite of eugenol[3], methyl eugenol[5] and chavibetol.
Xanthine Oxidase Inhibitor
Hydroxychavicol is an extremely potent xanthine oxidase inhibitor with an IC50 value 0.0167 µM.[2] Its more potent than allopurinol (IC50 0.0307 µM).[2]
Platelet Aggregation Inhibitor
Tests performed found hydroxychavicol was an inhibitor of platelet aggregation in vitro.[4]
COX-1/COX-2 inhibitor
Hydroxychavicol was found to be a potent inhibitor of COX-1 and COX-2 in vitro.[4]
Chemical Properties
Synonyms: 1,2-dihydroxyallylbenzene; 1,2-dihydroxy-4-allylbenzene; 2-hydroxychavicol
PubChem Compound ID: 70775
Molecular Weight: 150.1745 [g/mol]
Molecular Formula: C9H10O2
XLogP3: 0.8
IUPAC Name: 4-prop-2-enylbenzene-1,2-diol
InChI: InChI=1S/C9H10O2/c1-2-3-7-4-5-8(10)9(11)6-7/h2,4-6,10-11H,1,3H2
InChIKey: FHEHIXJLCWUPCZ-UHFFFAOYSA-N
Canonical SMILES: C=CCC1=CC(=C(C=C1)O)O