Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. GAD uses PLP as a cofactor.
Inducers (in vitro rat brain)
Inhibitors (in vitro rat brain)
1. Awad R, Levac D, Cybulska P, Merali Z, Trudeau VL, Arnason JT.Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system.; Ottawa-Carleton Institute of Biology, University of Ottawa, Ottawa, ON K1N6N5, Canada.; Can J Physiol Pharmacol. 2007 Sep;85(9):933-42. PubMed PMID: 18066140
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