Enzymes are large biological molecules responsible for many chemical interconversions that sustain life. Many enzymes present in humans can activate and inactivate drugs. In many cases multiple enzymes are at play.
The Olahuasca Activation theory outlines several steps used which inhibit and induce several human enzymes in order to produce psychedelic effects from several allylbenzenes which are normally inactivated by human enzymes.
The Amazonian Ayahuasca tea used by thousands uses Banisteriopsis caapi to inhibit MAO-A enzymes to produce psychedelic effects from plant admixtures containing the illegal drug DMT which is normally inactivated by human MAO-A enzymes.
Enzymes covered on HerbPedia
- Alanine Aminotransferase
- Alcohol Dehydrogenase
- Aldehyde Dehydrogenase (ALDH)
- Aldehyde Oxidase
- Aldose Reductase
- Cytochrome P450
- Estradiol 17beta-dehydrogenase Type 2
- Glucuronosyltransferase (UGT)
- Glutamate Decarboxylase
- Glutathione S-Transferase (GST)
- Monoamine Oxidase A
- Monoamine Oxidase B
- Semicarbazide-Sensitive Amine Oxidase
- Sulfotransferase (SULT)
- Xanthine Oxidase