Ellagic Acid

Ellagic Acid is an antioxidant found in pomegranate juice.

Ellagic acid is a potent inhibitor of glutathione S-transferase enzymes GSTA1-1, GSTA2-2, GSTM1-1, GSTM2-2, and GSTP1-1.[1]

Ellagic acid is a potent inhibitor of alcohol dehydrogenase.[2]

Ellagic acid is also a potent inhibitor of xanthine oxidase with an IC50 of 3.1 µM.

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Bibliography

1. The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin.

Hayeshi R, Mutingwende I, Mavengere W, Masiyanise V, Mukanganyama S. PubMed PMID: 17046132

2. Phytophenols in whisky lower blood acetaldehyde level by depressing alcohol metabolism through inhibition of alcohol dehydrogenase 1 (class I) in mice.

Haseba T, Sugimoto J, Sato S, Abe Y, Ohno Y. PubMed PMID: 19013301