CYP2J2 is expressed in the human small intestine and many extrahepatic tissues.
CYP2J2 is known to metabolize ebastine into hydroxyebastine and terfenadine into terfenadine alcohol.
Other CYP2J2 substrates include astemizole, linoleic acid, arachidonic acid and
|Potent Inhibitors||Strength||Dosage||Verified in Man|
|Moderate Inhibitors||Strength||Dosage||Verified in Man|
|Terfenadine Alcohol ||?||?||?|