Cinnamic acid is a metabolite of cinnamaldehyde created in humans by the action of aldehyde dehydrogenase.
The enzyme Phenylalanine ammonia-lyase (PAL, EC 4.3.1.5), is capable of converting cinnamic acid to L-phenylalanine. Using a culture medium of Rhodotorula glutinis containing PAL, at pH 10.0 cinnamic acid was aminated to L-phenylalanine, but at pH 8.8 L-phenylalanine was deaminated into cinnamic acid.[1]
| Substrate | PAL | Product |
|---|---|---|
| Cinnamic acid | pH 10 | L-phenylalanine |
|
 |
Chemical Properties
Synonyms: trans-cinnamic acid
PubChem Compound ID: 444539
Molecular Weight: 148.15862 [g/mol]
Molecular Formula: C9H8O2
XLogP3: 2.1
H-Bond Donor: 1
H-Bond Acceptor: 2
IUPAC Name: (E)-3-phenylprop-2-enoic acid
InChI: InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+
InChIKey: WBYWAXJHAXSJNI-VOTSOKGWSA-N
Canonical SMILES: C1=CC=C(C=C1)C=CC(=O)O
Isomeric SMILES: C1=CC=C(C=C1)/C=C/C(=O)O
