Alanine aminotransferase or ALT is a transaminase enzyme (EC 18.104.22.168).
Using pyridoxal phosphate (P5P) as a coenzyme, and the amino acid alanine, ALT is able to convert compounds with a keto (C=O) group into amines (C-NH2).
- ALT catalyzes the following enzymatic reaction
- glutamate + pyruvate ⇌ α-ketoglutarate + alanine
Inhibitors of ALT in Humans in Vivo
Inducers of ALT in Rats in Vivo
Star fruit juice 
1. Evidence for both in vivo and in vitro interaction between vigabatrin and alanine transaminase.
Richens A, McEwan JR, Deybach JC, Mumford JP. PubMed PMID: 9131948
2. Evaluation of the toxic effect of star fruit on serum biochemical parameters in rats
Z. Y. Khoo, C. C. Teh, N. K. Rao, and J. H. Chin PubMed PMCID: PMC2900059
page revision: 5, last edited: 09 Feb 2013 08:16