In vitro 6-Methoxy-DMT was found to bind to human 5-HT(2) receptor sites. It also binds to human 5-HT(6) receptor sites.
In vitro tests found that 6-Methoxy-DMT bound to rat 5-HT(2A) receptor sites with approximately 1/12 the affinity of DMT, but it's binding affinity was approximately 3 times stronger towards 5-HT(1A) at approximately 1/6 the affinity of DMT.
It's action in man appears to be untested.
The corresponding allylbenzene alkaloid metabolite of this molecule is 1'-oxoestragole-DMA.
Synonyms: 6-MeO-DMT; 6-OMe-DMT; 6-Methoxy-N,N-dimethyltryptamine
ChemSpider ID: 23118889
PubChem Compound ID: 12017579
Molecular Weight: 218.29482 [g/mol]
Molecular Formula: C13H18N2O
H-Bond Donor: 1
H-Bond Acceptor: 2
IUPAC Name: 2-(6-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine
Canonical SMILES: CN(C)CCC1=CNC2=C1C=CC(=C2)OC
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