
In vitro 6-Methoxy-DMT was found to bind to human 5-HT(2) receptor sites.[1] It also binds to human 5-HT(6) receptor sites.
In vitro tests found that 6-Methoxy-DMT bound to rat 5-HT(2A) receptor sites with approximately 1/12 the affinity of DMT, but it's binding affinity was approximately 3 times stronger towards 5-HT(1A) at approximately 1/6 the affinity of DMT.[2]
It's action in man appears to be untested.[2]
The corresponding allylbenzene alkaloid metabolite of this molecule is 1'-oxoestragole-DMA.
Chemical Properties
Synonyms: 6-MeO-DMT; 6-OMe-DMT; 6-Methoxy-N,N-dimethyltryptamine
ChemSpider ID: 23118889
PubChem Compound ID: 12017579
Molecular Weight: 218.29482 [g/mol]
Molecular Formula: C13H18N2O
XLogP3: 2.7
H-Bond Donor: 1
H-Bond Acceptor: 2
IUPAC Name: 2-(6-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine
InChI: InChI=1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-8-11(16-3)4-5-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3
InChIKey: AWOWBKXVYZRYSP-UHFFFAOYSA-N
Canonical SMILES: CN(C)CCC1=CNC2=C1C=CC(=C2)OC
See Also
- 1'-Oxoestragole
- 1'-Oxoestragole-DMA
- 1'-Oxoestragole-PEA
- 6-methoxy-DMT
- Methoxy Chavicol
- Oilahuasca Activation