1'-Hydroxyelemicin Glucuronide

1'-Hydroxyelemicin glucuronide is a metabolite of elemicin created from the intermediate metabolite 1'-hydroxyelemicin by the action of glucuronosyltransferase (UGT). The UGT enzymes UGT2B7 and UGT1A9 were found to perform this action on the related compound 1'-hydroxyestragole and are assumed to also carry out this action on 1'-hydroxyelemicin, but it's possible other UGT enzymes perform this action.

Substrate UGT End Product
1'-Hydroxyelemicin 1'-Hydroxyelemicin glucuronide
1-Hydroxyelemicin.gif 1-Hydroxyelemicin_Glucuronide.png
Cofactor Byproduct
UDPglucuronate UDP
UDPglucuronate.png UDP.png

Chemical Properties

Molecular Weight: 400.42 [g/mol]
Formula: C18H24O10
XLogP3: 0.45[1]
Canonical SMILES: O(C1[CH]([C@H]([CH]([C@H](O1)C(=O)O)O)O)O)C(C2=CC(=C(C(=C2)OC)OC)OC)C=C

1. XLogP3 values calculated using the Virtual Computational Chemistry Laboratory's
On-line Lipophilicity(logP), Water Solubility(LogS) & pKa Prediction calculator.
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